BUTISOL SODIUM® (butabarbital sodium tablets, USP and butabarbital sodium oral solution, USP) would be the sodium salt of a weak acid. Barbiturates are weak acids which can be absorbed and quickly dispersed to all tissues and fluids with high concentrations from the Mind, liver, and kidneys.

Tricyclic Antidepressants: Barbiturates may increase the metabolism of Tricyclic Antidepressants. Administration: Check for reduced efficacy of tricyclic antidepressants if a barbiturate is initiated/dose increased, or greater results if a barbiturate is discontinued/dose lessened. Tricyclic antidepressant dose changes are very likely necessary. Consider therapy modification

butabarbital will minimize the level or effect of tadalafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Steer clear of mixture in pulmonary HTN people. For individuals with ED, check reaction to tadalafil meticulously due to potential for reduced usefulness.

butabarbital will minimize the extent or outcome of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

The impact of the resultant lowered blood levels of griseofulvin on therapeutic reaction hasn't been recognized. Even so, it would be preferable to stay away from concomitant administration of these medications.

butabarbital will minimize the extent or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. No dosage adjustment for ondansetron is usually recommended for sufferers on these prescription drugs.

butabarbital will lower the extent or effect of parecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Check.

butabarbital will lower the extent or outcome of clozapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

butabarbital will reduce the level or impact of quetiapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

butabarbital will lower the extent or effect of losartan by affecting hepatic enzyme CYP2C9/10 metabolism. Small/Importance Mysterious.

butabarbital will lower the level or result of pantoprazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

butabarbital will lower the extent or impact of clarithromycin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.

butabarbital will reduce the extent or result of phenytoin by impacting hepatic enzyme read more CYP2C9/10 metabolism. Use Warning/Watch.

butabarbital will decrease the extent or result of sufentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.